2 PhD Fellow at University of Groningen

2 PhD fellows schizophrenia project
University of Groningen, The Netherlands
Vacancy number: 207176/77

Job descriptionTOP Institute Pharma (TI Pharma) has granted our proposal to set up the mechanism-based PK-PD modeling platform. This platform focuses on the transfer of knowledge from academia to the pharmaceutical industry and is a collaborative effort of 4 academic partners and 6 industrial partners. Unique to this platform is the availability of shared databases.

The aim of the platform is to provide a scientific basis for rational drug discovery and development with a strong focus on priority medicines. Challenges are to predict disease progression, the effects of ageing, combined drug effects and to translate preclinical data to clinical data through the construction of mechanism-based PK/PD models. Existing anonimized (pre-) clinical data will be analyzed with advanced data analysis software tools such as NONMEM and S+ or R.

The translational research working group addresses cardiovascular safety and schizophrenia. Within the schizophrenia project we are looking for 2 PhD fellows.

You will work as a team member of a TI Pharma project. The project team comprises academic and industrial partners. In this case, the partners are: universities of Leiden and Groningen, the University Medical Center of Utrecht, the Erasmus Medical Center and the companies Eli Lilly, Johnson & Johnson, GSK, Nycomed, Organon and Pfizer. You will attend a unique drug discovery education and training program offered by TI Pharma.

Requirements
* Master degree in Biomedical Sciences, Pharmaceutical Sciences, Life Science and Technology, Mathematics, Statisticsor Theoretical Biology
* Preferably a background in Model Building and the Pharmaceutical Sciences
* Profound interest in Model Building
* Ambitious
* Creative
* Interested to perform research in a unique multidisciplinary setting

Organization

The University of Groningen is a university with a high reputation for academic teaching and research and a large international network The vacancy is at the Department of Pharmacokinetics and Drug Delivery. This department is part of the University Centre for Pharmacy, and participates in the research school Groningen University Institute for Drug Exploration (GUIDE).

of Groningen offers an appointment for a period of four years which period should be finished with a Ph.D. examination. During the first year the gross salary is ¤ 1956,= per month. This amount will increase to ¤ 2502= during the fourth year. After one year, the performance of the candidate will be evaluated to decide whether there is sufficient progress to expect a successful completion of the Ph.D. thesis within the remaining three years. A training programme is part of the agreement. You and your supervisor will make up a plan for the additional education and supervising that you specifically need. This plan also defines your teaching activities.

Additional InformationAdditional information can be obtained from dr. J.H. Proost Department of Pharmacokinetics and Drug Delivery, University of Groningen ( j.h.proost@rug.nl ), tel +31 50 363 3292 (secretariat tel. +31 50 363 3272).

ApplicationApplications with curriculum vitae and the names of 3 persons that can be contacted as references should be sent before November 1, 2007, to:
University of GroningenPersonnel and Organization DepartmentP.O. Box 729700 AB Groningen, The Netherlandsemail: vmp@bureau.rug.nl